effect of ketoprofen transdermal patch applied 30 minutes before lower limb surgeries under spinal anaesthesia to see its pain relief effect after surgery

Effect of Pre-emptive analgesia with Ketoprofen Transdermal patch (30 mg) on post-operative pain for lower limb surgeries under subarachnoid Block - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056940

Enrollment

Registered

2023-08-25

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: preemptive ketoprofen transdermal patch for post operative pain: ketoprofen transdermal patch 30 mg to be applied on non hairy skin of left shoulder 1 hour before surgery and post opera

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I and II. 2. Both gender of age 18-65 years. 3. Patients for lower limb surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: 1. Patients with hypersensitivity to study drugs, NSAID’s group and transdermal patch-es. 2. Patients with history of skin diseases. 3. Patients with history of asth-ma, gastrointestinal disor-ders, blood coagulopathy, cardiovascular diseases. 4. History of CNS, hepatic and renal disorders. 5. Patients with history of drug abuse. 6. Any contraindication for spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of Pre-emptive Analgesia with Ketoprofen transder-mal patch (30 mg) on post-operative pain by VAS (Visual Analogue Scale) score in 24 hoursTimepoint: 24 hours	—

Secondary

Measure	Time frame
To evaluate the effect of Pre-emptive Analgesia with Ketoprofen transder-mal patch (30 mg) on post-operative pain for lower limb surgeries under Subarachnoid Block with regard to- 1. Duration of analgesia 2. Total consumption of rescue analgesic in 24 hrs. 3. Patient satisfaction score by Likert’s 5-point satisfaction scale & patient anxiety score by VAS score. Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactUC Verma

School of Medical Sciences and Research Sharda University

uttam.verma@sharda.ac.in9968604211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026