Health Condition 1: K002- Abnormalities of size and form ofteeth
Conditions
Interventions
Intervention1: Preadjusted Edgewise Appliance with i PRF: The blood collected in vials will be centrifuged at 700 rpm for 3 minutes at room temperature. After centrifugation blood will be separated in
Red blood cells at bottom part and yellowish liquid Platelet-rich Fibrin in the upper part. 2-3 mL liquid portion from the upper part will be drawn into disposable insulin syringe and the bottom part
Sponsors
Dr JN Rupa
Eligibility
Inclusion criteria
Inclusion criteria: patient with Class I / half cusp Class II malocclusion cases with moderate to severe crowding in maxillary arch ( >6mm Little’s Irregularity Index).No previously reported or observed active orthodontic treatment. Completed root apexification assessed with periapical radiographs. Patients with healthy periodontium and no gingival inflammation at the experimental sites. Patients with positive informed consent.
Exclusion criteria
Exclusion criteria: patient with Platelet count less than normal 150000 per µl of blood. Patients on regular antibiotics, steroids or anti-inflammatory drugs. Signs of external apical root shortening observed at the preoperative radiographic examination. Non- compliant patient with poor oral hygiene. Syndromic patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimate and compare levels of DSPP in GCF at different interval of time during alignment of maxillary incisors with and without i-PRF injection.Timepoint: preoperative, before anterior alignment, 4 weeks, 8 weeks,3 month, 4 month, 6 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To estimate the amount and extent of root resorption in the maxillary incisors after alignment with and without i-PRF injection using CBCT.Timepoint: preoperative and postoperative | — |
Countries
India
Contacts
Public ContactDr JN Rupa
centre for dental education and research
Outcome results
None listed