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Brain stimulation in post-polio syndrome patients to assess functional and psychological parameters; A randomised controlled trial.

A study of intermittent Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex on Post-Polio Syndrome. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056927
Enrollment
18
Registered
2023-08-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere

Interventions

Intervention1: Non invasive brain stimulation: The Post-polio syndrome(PPS) patients will be categorized into 3 groups:- 1. Group 1 consists of patients with PPS recieving Repetitive Transcranial Magn

Sponsors

Department of Physiology, AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with post-polio syndrome diagnosed according to European Federation of the Neurological Societies (EFNS) guidelines (Farbu et al.,2006) as diagnostic criteria. 2. Age of patients: 25-80 years of any gender.

Exclusion criteria

Exclusion criteria: 1. All other treatable conditions causing muscle fatigue and/or wasting 2. Myopathies of any other origin 3. Any other motor neuron disorders 4. Psychiatric disorders 5. Pregnancy and lactation 6. History/ family history of seizures 7. Cardiac pacemaker or any ferromagnetic metallic implants close to target of stimulation area 8. Acute eczema/bed sore under target of stimulation area 9. Ventilator dependent and tracheostomy patients

Design outcomes

Primary

MeasureTime frame
Motor function by using 25 feet walk testTimepoint: Pre-intervention (baseline) Post-intervention (after 8 sessions; twice a week for 4 weeks)

Secondary

MeasureTime frame
1. Motor function (Manual muscle testing, Activities of Daily Life scale- Barthel Index, Upper or lower limb Motor Threshold & Motor Evoked Potentials) 2. Fatigue (Fatigue Severity Scale, Modified Fatigue Impact Score) 3. Depression & Anxiety (Hamilton Rating Depression Scale, State-Trait Anxiety Inventory) Timepoint: Pre-intervention (baseline) Post-intervention (after 8 sessions)

Countries

India

Contacts

Public ContactDEEPALI RANA

AIIMS New Delhi

deepalirana40@gmail.com9711408597

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026