Dexmedetomidine instilled in urinary bladder for prevention of post-operative catheter related bladder discomfort in renal transplant patients.

Intravesical Dexmedetomidine for prevention of post-operative catheter related bladder discomfort in renal transplant recipients- a prospective randomized double-blind, placebo-controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056908

Enrollment

Registered

2023-08-24

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Dexmedetomidine group: 2.5ug/kg dexmedetomidine in 100ml Normal Saline will be introduced once via Foleys catheter before the surgery begins. The catheter will then be clamped for 30-40

Eligibility

Inclusion criteria

Inclusion criteria: End Stage Renal Disease patients about to undergo Renal Transplant Surgery.

Exclusion criteria

Exclusion criteria: Patients with history of outflow obstruction, transurethral resection of prostate for benign prostatic hyperplasia, history of bladder catheterization within last 6 months, re look Percutaneous Nephrolithotomy, Pre-existing percutaneous nephrostomy , overactive bladder (frequency >3 times in the night or >8 times in 24 h), morbid obesity, disturbance of the central nervous system, chemical substance abuse or any psychiatric disease.

Design outcomes

Primary

Measure	Time frame
Incidence of Cathedral Related Bladder Discomfort (CRBD) in each group.Timepoint: 2 hours post surgery	—

Secondary

Measure	Time frame
Incidence of Cathedral Related Bladder Discomfort (CRBD) in each group.Timepoint: 0, 4, 12 & 24 hours post surgery.;Severity of CRBDTimepoint: 0,2,4,12,and,24 hours post surgery.;Incidence of postoperative nausea vomiting (PONV)Timepoint: 0,2,4,12 & 24 hours post surgery	—

Countries

India

Contacts

Public ContactDivya Srivastava

Sanjay Gandhi Post Graduate Institute of Medical Sciences

dr.divshri@gmail.com07839098150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026