Skip to content

A clinical study to evaluate the fluid response in patients undergoing neurosurgery.

Tidal volume challenge to predict fluid responsiveness during neurosurgery in sitting position with low tidal volume ventilation. - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056880
Enrollment
42
Registered
2023-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere

Interventions

Intervention1: NIL: NIL Intervention2: NIL: NIL Control Intervention1: NIL: NIL Control Intervention2: NIL: NIL

Sponsors

AIIMS New delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All elective neurosurgical patients (age >18 years, ASA I II) requiring sitting positioning will be considered eligible.

Exclusion criteria

Exclusion criteria: o Any recurrent cardiac arrhythmia; reduced ventricular systolic function - left (ejection fraction o BMI more than 30 o Intra-operative use of vasopressors or inotropes before or during TVC o Chronic lung disease o Pre-operative use of beta blocking agents.

Design outcomes

Primary

MeasureTime frame
To assess the reliability of changes in pulse pressure variation (PPV) & stroke volume variation (SVV) values induced by tidal volume challenge in predicting fluid responsiveness in patients undergoing neurosurgery in the sitting position under 6 ml/kg (PBW)Timepoint: To assess the reliability of changes in pulse pressure variation (PPV) & stroke volume variation (SVV) values induced by tidal volume challenge in predicting fluid responsiveness in patients undergoing neurosurgery in the sitting position under 6 ml/kg (PBW)

Secondary

MeasureTime frame
To assess the reliability of pulse pressure variation (PPV) & stroke volume variation (SVV) at 6 ml/kg & 8 ml/kg.Timepoint: Starting point - At the point when sitting postion of the patint is achieved with hemodynamic stability. End Point - At the point when Hemodynamic parameters are noted after the fluid challenge.

Countries

India

Contacts

Public ContactDr Niraj Kumar

AIIMS new delhi

drnirajaiims@gmail.com09013770806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026