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To evaluate if Procalcitonin is a reliable marker to diagnose Sepsis Syndrome in oral and maxillofacial infections.

Appraisal of accuracy of Procalcitonin in Maxillofacial Infections to Diagnose Sepsis Syndrome - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056876
Enrollment
30
Registered
2023-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A488- Other specified bacterial diseases

Interventions

Intervention1: Serum Procalcitonin test: Before starting the antibiotic treatment and at the time of discharge Control Intervention1: NOT APPLICABLE: NOT APPLICABLE

Sponsors

DrNupoor Sanjaykumar Meher
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with swelling of the face and/or neck that suggested an abscess or cellulitis complaining of one or more of the following symptoms: a compromised airway, restricted mouth opening, dysphagia, or body temperature greater than 38 °C will be admitted and will be included in the study.

Exclusion criteria

Exclusion criteria: Patient unwilling to be a part of the study. Patients with non-maxillofacial infection. Known cases of neuroendocrine tumors, medullary thyroid cancer, small cell lung cancer, carcinoid syndrome, noninfectious systemic inflammation like inhalational injury, pulmonary aspiration, pancreatitis, heat stroke, mesenteric infarction, trauma, mechanical injury, burns, recent surgery.

Design outcomes

Primary

MeasureTime frame
Procalcitonin level can be increased at the time of admission due to presence of active infection The level can define the status of systemic spread of infection & aid to decide the antibiotic regimeTimepoint: PCT test will be done at the time of admission

Secondary

MeasureTime frame
Procalcitonin level can be decreased at the time of discharge due drainage of pus & administration of antibiotics Antibiotics can be stopped after PCT level is decreased to avoid antibiotic resistance due to overdosageTimepoint: PCT test will be done at the time of discharge

Countries

India

Contacts

Public ContactDr.Nupoor Sanjaykumar Meher

Bharati Vidyapeeth Dental College and Hospital, Pune

vikrantsane@gmail.com09860721934

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026