Comparison of opioid versus opioid free anaesthesia with ketamine and lidocaine on post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

Comparative evaluation of opioid versus opioid free anaesthesia with ketamine and lidocaine on post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056869

Enrollment

110

Registered

2023-08-24

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparative evaluation of opioid versus opioid free anaesthesia with ketamine and lidocaine on post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: Co

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I and II 2. Age 18-60yrs 3. Both genders 4. Surgeries = 2 hours

Exclusion criteria

Exclusion criteria: 1. BMI > 30 kg m¬-2 2. Pregnant females 3. Patients having history of motion sickness and migraine. 4. Patients having history of drug allergy to ketamine and lidocaine. 5. Patients having history of respiratory, cardiovascular, renal, hepatic and endocrine disease and psychosis.

Design outcomes

Primary

Measure	Time frame
To compare the effect of fentanyl (opioid) versus ketamine & lidocaine (opioid free) anaesthesia on post-operative nausea and vomiting in laparoscopic cholecystectomy.Timepoint: Post operative 24 hours	—

Secondary

Measure	Time frame
To compare the effect of fentanyl (opioid) versus ketamine & lidocaine (opioid free) anaesthesia in laparoscopic cholecystectomy with regard to: 1. VAS Score for post-operative pain. 2. Duration of analgesia in post-operative period. 3. Sedation score postoperatively. 4. The duration of discharge from PACU. Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactUC Verma

Department of Anaesthesiology School of Medical Sciences & Research Sharda University

uttam.verma@sharda.ac.in9968604211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026