A comparison of two additive drugs to conventional local anesthesia in patients undergoing upper limb surgeries under regional anaesthesia.

A randomized controlled trial to study effectiveness of nalbuphine vs dexmedetomidine as an adjuvant to local anaesthesia in patients undergoing Upper limb surgeries under ultrasound guided supraclavicular block. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056862

Enrollment

Registered

2023-08-24

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Ropivacaine, lignocaine and Normal Saline: Group A: Receives ropivacaine plain 0.5 % 10 ml +lignocaine plain 2 % 5 ml +10ml Normal saline (NS) Duration: Intraoperative Intervention2: Ro

Group C: Receive ropivacaine plain 0.2 % 10 ml +lignocaine plain 2 % 5 ml + Nalpbuphine 10 mg diluted in 10 ml NS. Control Intervention2: NOT APPLICABLE: NOT APPLICABLE Control Intervention3: NOT APPL

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I & II Patient undergoing upper limb orthopaedic surgeries

Exclusion criteria

Exclusion criteria: 1. Patients are unwilling 2. Patients with bleeding disorders, 3. Patients on anticoagulants, 4. Patients with neurological and musculoskeletal disease, 5. Infection at the site of injection 6. History of allergy to local anaesthetics

Design outcomes

Primary

Measure	Time frame
To compare:- (a)The onset of sensory and motor blockade. (b)The duration of sensory and motor blockade. Timepoint: (a)Immediately after positioning the patient supine and every 5 minutes to check for onset of sensory and motor blockade (b)In the post operative period NRS score for pain, SpO2, sensory and motor weakness, requirement of rescue analgesia, will be noted during following intervals: 0-2 hours, 4-6 hours, 6-12 hours, 12-24 hours.	—

Measure

Time frame

To compare:- (a)The onset of sensory and motor blockade. (b)The duration of sensory and motor blockade. Timepoint: (a)Immediately after positioning the patient supine and every 5 minutes to check for onset of sensory and motor blockade (b)In the post operative period NRS score for pain, SpO2, sensory and motor weakness, requirement of rescue analgesia, will be noted during following intervals: 0-2 hours, 4-6 hours, 6-12 hours, 12-24 hours.

—

Secondary

Measure	Time frame
Intraop & post op side effects & complications Timepoint: Immediately after positioning of patient uptil the surgery is finished. In the post operative period, Basal hemodynamics (HR, NIBP) & SpO2, requirement of rescue analgesia, nausea, vomiting will be noted during following intervals: 0-2 hours, 4-6 hours, 6-12 hours, 12-24 hours.	—

Countries

India

Contacts

Public ContactVIDHU BHATNAGAR

INSTITUTE OF NAVAL MEDICINE, INHS ASVINI

vizardsvids@gmail.com9969777168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026