Does vitamin D3 has any effect in preventing preeclampsia and its complication in pregnant females

Efficacy and safety of vitamin D3 supplementation in the prevention of pre-eclampsia and associated complications: A randomized controlled clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056852

Enrollment

Registered

2023-08-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Vitamin D3: The intervention group will receive vitamin D supplementation according to their serum vitamin D levels in addition to the Standard of care as per guidelines for pregnant fe

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant females who are willing to give written informed consent to participate in the study. 2. Pregnant females of age group 21-35 years with a singleton pregnancy and with a gestation age of 18-19 weeks.

Exclusion criteria

Exclusion criteria: 1. Pregnant females who are unable or unwilling to give written informed consent. 2. Fetal abnormalities in the current or previous pregnancy 3. History of recurrent miscarriage 4. History of pre-eclampsia 5. History of hypertension 6. Twin pregnancy 7. Chronic kidney and liver disease 8. History of malignancy 9. Known case of osteomalacia 10. Recent history of therapeutic vitamin D3 consumption other than supplementation in the study 11. History of seizures 12. Known case of Diabetes mellitus

Design outcomes

Primary

Measure	Time frame
Pre-eclampsia assessment by blood pressure & proteinuriaTimepoint: Baseline 24 weeks, 28 weeks, 32 weeks & 36 weeks of gestation	—

Secondary

Measure	Time frame
Serum vitamin D & calcium levels, kidney function tests, liver function tests, lipid profile and cordblood vitamin D levelsTimepoint: Baseline & 36 weeks	—

Countries

India

Contacts

Public ContactDr Savita

BPS Govt. Medical College Khanpur Kalan, Sonipat

garimaahuja2010@yahoo.com9992108132

Outcome results