Balanced crystalloids vs unbalanced crystalloids in patients with dengue shock syndrome

Comparison of normal saline vs plasmalyte on serum chloride levels in Dengue Shock Syndrome in children - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056814

Enrollment

Registered

2023-08-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A91- Dengue hemorrhagic fever

Interventions

Intervention1: Plasmalyte A: Children in PL group will be started with 10-20ml/kg bolus in intial 30 mins, if the hematocrit falls, pulse rate and blood pressure stable and urine output between 0.5 to

Eligibility

Inclusion criteria

Inclusion criteria: Children from 2 months to 18 years admitted at Government Medical College and Hospital, Chandigarh

Exclusion criteria

Exclusion criteria: 1) Children already received fluids from outside before enrolment in last 6h 2) Children with cardiogenic shock 3) Known patient with chronic kidney disease 4) Severe Malnutrition 5) Children whose parents deny consent

Design outcomes

Primary

Measure	Time frame
greater than equal to 5mmol/L increase in serum chloride level within 48 hours (h) post- randomization.Timepoint: time of randomisation and 48 hours post randomisation	—

Secondary

Measure	Time frame
hospital stay duration, need for colloid bolus, incidence of hyponatremia, new-onset AKI, standard base excess, serum lactate levels, renal replacement therapy.Timepoint: during hospital stay	—

Countries

India

Contacts

Public ContactDr. Vidushi Mahajan

Government Medical and Hospital, Chandigarh

vidushimahajan2003@gmail.com7405517216

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026