Compare the pain relief effect of dexmedetomidine and dexamethasone as an additive to ropivacaine in ultrasound guided block for gall bladder surgeries

Compare the analgesic effect of dexmedetomidine and dexamethasone as an adjuvant to ropivacaine in ultrasound guided erector spinae plane block for laparoscopic cholecystectomy - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056800

Enrollment

Registered

2023-08-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K81- Cholecystitis

Interventions

Intervention1: Ultrasound(USG)guided Erector Spinae Plane Block (ESPB) [0.2% ropivacaine with dexamethasone(10mg)]: USG guided ESPB will be given bilaterally to patients undergoing laparoscopic chole

Eligibility

Inclusion criteria

Inclusion criteria: 1)18 to 65 years of age undergoing laparoscopic cholecystectomy 2)Patients of ASA I and II.

Exclusion criteria

Exclusion criteria: 1)Patient refusal. 2)Bleeding diathesis. 3)Local skin infection at the site of block. 4)Psychiatric disorder or risk of psychiatric disease. 5)Laparoscopic cholecystectomy turned to open cholecystectomy. 6)Any allergy to local anaesthetics or adjuvants dexmedetomedine/dexamethasone.

Design outcomes

Primary

Measure	Time frame
Postoperative pain using NRS score at various time intervals in both groups.Timepoint: 0 mins 30 mins 1 hours 2 hours 6 hours 12 hours 24hours	—

Secondary

Measure	Time frame
1)The time at which the first rescue analgesia will be requested post operatively in both groups 2) Total amount of analgesic consumption within 24 hours postoperatively in both groups 3) Time of initiation of ambulation. 4) Respiratory Function(FEV1, FVC, FEV1/FVC & PEFR) pre-operatively and24hrspost-operatively using hand held spirometer. 5) Incidence of PONV. 6) Patient satisfaction. Timepoint: Within 24 hr	—

Measure

Time frame

1)The time at which the first rescue analgesia will be requested post operatively in both groups 2) Total amount of analgesic consumption within 24 hours postoperatively in both groups 3) Time of initiation of ambulation. 4) Respiratory Function(FEV1, FVC, FEV1/FVC & PEFR) pre-operatively and24hrspost-operatively using hand held spirometer. 5) Incidence of PONV. 6) Patient satisfaction. Timepoint: Within 24 hr

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Countries

India

Contacts

Public ContactEzhukattil Reshma James

Maulana Azad Medical College

nprasadgovil@yahoo.com7982903955

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026