Health Condition 1: A488- Other specified bacterial diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients (= 18 years) admitted for sepsis or septic shock( according to Sepsis-3 criteria) within 24 hours after admission in the department of critical care medicine
Exclusion criteria
Exclusion criteria: (1) Under 18 years of age. (2) Pregnancy. (3) Shock of other origin. (4) Acute coronary syndrome, chronic renal disease, chronic liver disease. (5) Malignancy. (6) On immunosuppressive therapy, HIV. (7) Leucopoenia. (8) Trauma, burn. (9) Post surgical patients/ patients requires immediate surgical intervention (10) Resuscitation status from cardiopulmonary arrest, (11) Antibacterial therapy in the 5 days prior to enrolment, (12) Do-not-resuscitate status. (13) Previous hospital admission within 4 week. (14) Patient taking any anticoagulant and/or Metformin. (15) History of coagulopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -To identify any correlation between biomarkers of sepsis (within 24 hrs after icu admission) and 28-day mortality due to sepsis or septic shock. Timepoint: 28 DAYS | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify any correlation between biomarkers of sepsis (within 24 hrs after icu admission) and duration of hospital stay. - To identify any correlation between biomarkers of sepsis(within 24 hrs after icu admission) and degree of organ involvement. - To identify early predictor of sepsis related mortalityTimepoint: 28 DAYS | — |
Countries
India
Contacts
IPGMER and SSKM Hospital