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Study of microRNA in Pulmonary Tuberculosis

Patterns in upregulation and downregulation of microRNA in clinical subtypes of Pulmonary Tuberculosis and their correlation with the course of illness - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056740
Enrollment
30
Registered
2023-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A150- Tuberculosis of lung

Interventions

Control Intervention1: nil: nil

Sponsors

Dr Swathy Moorthy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: cohort 1A : sputum positive Pulmonary Tuberculosis patients who will be classified as cavitatory type on chest X ray or CT scan cohort 1B : sputum positive Pulmonary Tuberculosis patients who will be classified as non cavitatory type - no cavity on chest X ray or CT scan

Exclusion criteria

Exclusion criteria: age more than 60 and less than 18 years, current smoking or alcoholism, presence of any prior chronic medical illness, pregnancy, drug resistant tuberculosis, tuberculosis patients with HIV co-infection, previously treated with ATT or other active lung infection like community acquired pneumonia, on steroids, anti inflammatory, anti convulsants, anti cancer drugs

Design outcomes

Primary

MeasureTime frame
get the microRNA profile of sputum positive Pulmonary Tuberculosis patientsTimepoint: at the end of two years once all sample are collected analysis will be done

Secondary

MeasureTime frame
identify the upregulated & downregulated microRNA in the sputum positive Pulmonary TuberculosisTimepoint: 3 years

Countries

India

Contacts

Public Contactdr Emmanuel Bhaskar

Sri Ramachandra Medical College, SRIHER

iec@sriramachandra.edu.in9840717971

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026