Health Condition 1: I824- Acute embolism and thrombosis of deep veins of lower extremity
Conditions
Interventions
Intervention1: injection.LMWH: This includes patient who are given Injection LMWH 0.4ml subcutaneously once daily for short duration (7days).
Control Intervention1: Injection LMWH: This includes patie
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with Caprini score = 4 undergoing major gynecological surgeries for the following indications: a. Benign conditions b. Conditions with Suspicion of malignancy c. Malignant conditions 2.Signed informed consent to participate in the study
Exclusion criteria
Exclusion criteria: 1.Patients with known contraindications for anticoagulants therapy. 2.History of venous thromboembolism in previous 6 months 3.Severe chronic kidney disease. 4.DVT/Pulmonary embolism prior to surgery 5.Severe peripheral arterial insufficiency (absence of a palpable pulsation in the dorsalis pedis artery), 6.Pregnancy 7.Allergy to radiographic contrast medium, acid sulfite or LMWH, 8.Hepatic insufficiency, 9.Acute stroke within the last 3 months 10.Gastrointestinal bleeding within the last month 11.Hemorrhagic diathesis 12.Patients already on anticoagulation treatment (including heparin, and vitamin K antagonists, but not antiplatelet treatment), 13.Thrombocytopenia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of short course v/s extendd course of LMWH in preventing post operative VTE among patients undergoing major gynecological surgeriesTimepoint: assessed at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To calculate the incidence of major bleeding episodes among the two groups.Timepoint: assessed at 3 months | — |
Countries
India
Contacts
Public ContactDr Garima Yadav
AIIMS Jodhpur
Outcome results
None listed