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Randomized treatment trial for adenoviral conjunctivitis

Comparison of Tobramycin/ Dexamethasone combination Eye drop versus Artificial Eye drops for the management of Presumed Viral Epidemic Conjunctivitis: A Randomized Treatment Trial - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056723
Enrollment
198
Registered
2023-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H102- Other acute conjunctivitis

Interventions

Intervention1: Tobramycin and dexamethasone combination eyedrop: Patients will be assigned to one of two groups using a computer-generated random number table. Group A will receive a combination of to

Sponsors

Sadguru Netra Chikitsalaya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Treatment naïve patients with recent onset of the presumed viral conjunctivitis (presenting within 5 days) and consenting to participate in the study will be included.

Exclusion criteria

Exclusion criteria: Patients with age <8 years, diffuse hemorrhagic conjunctivitis, conjunctivitis having matted eyelashes/ purulent discharge/ membrane or pseudo membrane/ lid infections like stye and chalazion, corneal involvement, anterior segment inflammation, prior history of viral keratitis, glaucoma or steroid responder, who do not adhere to the study follow- up schedule and mentally subnormal patients who are unable to express symptoms severity will be excluded

Design outcomes

Primary

MeasureTime frame
The primary outcome is the proportion of patients getting complete relief (symptom score 0) in the ‘study eye’ after 48 hours & 7 days of starting treatment.Timepoint: 48 hours & 7 days of starting treatment

Secondary

MeasureTime frame
Partial relief in terms of reduction of symptom scoresTimepoint: 48 hours & 7 days of starting treatment;proportion of patients developing adverse events & the subsequent need for change in treatment.Timepoint: 48 hours & 7 days of starting treatment

Countries

India

Contacts

Public ContactAmruta More

Sadguru Netra Chikitsalaya

chintanshah21191@gmail.com9904490444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026