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Estimation of serum complement levels in chronic spontaneous urticaria as a novel disease marker and its correlation with the disease severity

Estimation of serum C3 and C4 levels in chronic spontaneous urticaria and its correlation with the disease severity - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056718
Enrollment
58
Registered
2023-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L509- Urticaria, unspecified

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

Father Muller research centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Non-smokers Patients diagnosed with active chronic spontaneous urticaria of more than or equal to 6 weeks duration.

Exclusion criteria

Exclusion criteria: 1. The subjects should not have taken oral corticosteroids or other immunosuppressive drugs in the last 8 weeks or antihistamines at least within 4 days before the day of assessment. 2. Patients with known complement deficiencies, recent trauma (

Design outcomes

Primary

MeasureTime frame
With this study, we may be able to indicate the role of complement proteins, C3 & C4 in the pathogenesis of CSU & assess its role in the prognosis of the disease severity. The knowledge derived from this study can help us develop a treatment system that caters to the severity of the disease process & further develop newer treatment options targeting C3, C4, which could be a promising option for the treatment of CSU. Timepoint: one year

Secondary

MeasureTime frame
The knowledge derived from this study can help us develop a treatment system that caters to the severity of the disease process & further develop newer treatment options targeting C3, C4, which could be a promising option for the treatment of CSU.Timepoint: 10 years

Countries

India

Contacts

Public ContactDr Swathi N

Father Muller Medical College

rameshderma@gmail.com9845084224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026