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Gene involvement and correlation in head & neck cancers

Clinical correlation of ERCC4 and ERCC5 gene polymorphism in squamous cell carcinoma of Head and Neck - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056688
Enrollment
100
Registered
2023-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Sir Sunder Lal Hospital BHU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Histologically proven squamous cell carcinoma of head and neck excluding nasopharynx, tumors of skin, sino-nasal tract, unknown primary

Exclusion criteria

Exclusion criteria: 1.Patients who has received any form of chemotherapy and radiotherapy in past 2.Pregnant or lactating women 3.Patients having previous history of cancer to any site 4.Controls having history of malignancy in the family 5.Patients having distant metastases

Design outcomes

Primary

MeasureTime frame
Polymorphism of ERCC4 & ERCC5 genes in histologically proven newly diagnosed untreated squamous cell carcinoma of Head & Neck cancer casesTimepoint: baseline(at presentation)—

Secondary

MeasureTime frame
• Clinical correlation of polymorphism with the disease presentation, treatment outcome & treatment related toxicitiesTimepoint: 2 months—

Countries

India

Contacts

Public ContactDr Ekta prakash

Institute of Medical Sciences BHU

ritushamishra@yahoo.co.in7376748436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026