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A clinical study to evaluate the fluid response in patients undergoing neurosurgery.

Tidal volume challenge to predict fluid responsiveness during neurosurgery in lateral position with low tidal volume ventilation, A prospective observational study. - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056665
Enrollment
42
Registered
2023-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

AIIMS New delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All elective neurosurgical patients (age >18 years, ASA I II) requiring lateral positioning will be considered eligible.

Exclusion criteria

Exclusion criteria: o Any recurrent cardiac arrhythmia; reduced ventricular systolic function - left (ejection fraction o BMI more than 30 o Intra-operative use of vasopressors or inotropes before or during TVC o Chronic lung disease o Pre-operative use of beta blocking agents.

Design outcomes

Primary

MeasureTime frame
To assess the reliability of changes in pulse pressure variation (PPV) and stroke volume variation (SVV) values induced by tidal volume challenge in predicting fluid responsiveness in patients undergoing neurosurgery in the lateral position under 6 ml/kg (PBW).Timepoint: Starting point - At the point when lateral postion of the patint is achieved with hemodynamic stability. End Point - At the point when Hemodynamic parameters are noted after the fluid challenge.

Secondary

MeasureTime frame
To assess the reliability of pulse pressure variation (PPV) and stroke volume variation (SVV) at 6 ml/kg and 8 ml/kg.Timepoint: Starting point - At the point when lateral postion of the patint is achieved with hemodynamic stability. End Point - At the point when Hemodynamic parameters are noted after the fluid challenge.

Countries

India

Contacts

Public ContactDr Niraj Kumar

ALL INDIA INSTITUTE OF MEDICAL SCIENCES (AIIMS) NEW DELHI

drnirajaiims@gmail.com09013770806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026