Health Condition 1: A488- Other specified bacterial diseases
Conditions
Interventions
Intervention1: M-MIST technique with PRF: PRF is considered a second-generation platelet concentrate
it has trimolecular fibrin morphology with a 74% composition of leukocytes, and is known to have osteoconductive, immunomodulatory, and neo-angiogenic properties. In vitro studies have demonstrated th
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1)25 years of age or older. 2)Stage II or III Periodontitis 3)Presence of at least a single site with PPD and clinical attachment level (CAL) =5 mm on the buccal surface associated with a 3-walled osseous defect depth of =3 mm bilaterally or in both maxillary and mandibular arches. 4)Adequate width of attached gingiva, 5)Plaque index
Exclusion criteria
Exclusion criteria: 1)Previous periodontal surgery within the last 6 months in area of interest. 2)Systemic conditions which are generally considered to be a contraindication to periodontal surgery. 3)Pregnant or lactating females 4)Current or former smokers. 5)Hopeless tooth. 6) Patients on systemic medications such as corticosteroids or Calcium channel blockers or taking long-term NSAIDS or taking bisphosphonates or calcium supplements. 7)patients who had periodontal sites with fractured and perforated roots 8) teeth with grade III mobility and furcation involvement 9) non-vital tooth with or without periapical pathology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in clinical attachment level and radiographic Defect depth reduction % from baseline to 6 months postoperativeTimepoint: baseline to 6 months postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing pocket depth plaque index modified sulcular bleeding index Early wound healing score patient VASTimepoint: 0,3 month, 6 month | — |
Countries
India
Contacts
Public ContactPeri srivani
SCB Dental College and Hospital
Outcome results
None listed