Comparison of nano silver fluoride and silver diamine fluoride in controlling cavities in special children

Comparative evaluation of cariostatic and antibacterial efficacy of nano silver fluoride with silver diamine fluoride in special children- a randomized controlled clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056614

Enrollment

Registered

2023-08-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nano silver fluoride: Nano silver fluoride will be applied in special children (Mentally challenged, IQ score â?? 35 to 70) of age 4 to 12 years with 3 to 4 carious primary or permanent

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children in the age group of 4-12 years 2. Presence of 3 to 4 active carious primary or permanent teeth with caries score 3,4 &5 of ICDAS II classification 3. Completion of informed consent to participate in the study by parents

Exclusion criteria

Exclusion criteria: 1. Caries with pulpal exposure or fistula and swelling 2. History of spontaneous or elicited pain from caries or showing any signs of pulpal infection, swelling, abscess, obvious discoloration of the tooth, or premature mobility 3. Reported usage of local or systemic antibiotics, chlorhexidine, or fluoride mouthwashes within the last 2 weeks 4. Children with 5 or more carious teeth. 5. Children who are undergoing medical treatment for chronic or acute diseases that affect salivary flow 6. Allergy or sensitivity to silver or any of the materials included in the study 7. Carious teeth in the exfoliative stage

Design outcomes

Primary

Measure	Time frame
1.Cariostatic effect of nano silver fluoride and silver diamine fluoride in 4 to 12-year-old specially abled children 2.Antibacterial effect of nano silver fluoride and silver diamine fluoride on salivary bacteria in 4 to12 year old specially abled children by measuring the microbial count of mutans streptococci and lactobacilli before and one month after intervention. Timepoint: 1.Cariostatic effect of nano silver fluoride and silver diamine fluoride in 1,3 and 6 months respectively 2.Antibacterial effect of nano silver fluoride and silver diamine fluoride on salivary bacteria before its application and after 1 and 3 months.	—

Measure

Time frame

1.Cariostatic effect of nano silver fluoride and silver diamine fluoride in 4 to 12-year-old specially abled children 2.Antibacterial effect of nano silver fluoride and silver diamine fluoride on salivary bacteria in 4 to12 year old specially abled children by measuring the microbial count of mutans streptococci and lactobacilli before and one month after intervention. Timepoint: 1.Cariostatic effect of nano silver fluoride and silver diamine fluoride in 1,3 and 6 months respectively 2.Antibacterial effect of nano silver fluoride and silver diamine fluoride on salivary bacteria before its application and after 1 and 3 months.

—

Secondary

Measure	Time frame
1.Safety of nano silver fluoride and silver diamine fluoride in 4 to 12 year old specially abled children.Timepoint: 18 Months	—

Countries

India

Contacts

Public ContactDr Nupur Ninawe

Government dental college and hospital, Nagpur

anijacekey916@gmail.com9400217916

Outcome results