Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified
Conditions
Interventions
Intervention1: dexamethasone group
: In preoperative room, patients will receive dexamethasone
8mg diluted in 100cc NS i.v. (group D ) infusion over
15 minutes one hour prior to the induction
Contr
Sponsors
Sir T general hospital
Eligibility
Inclusion criteria
Inclusion criteria: a prospective comparative randomized double blind controlled study, this randomized controlled clinical study will be carried out in patients in orthopedic operation theatre of sir T hospital ,government medical college , bhavnagar , Gujarat.
Exclusion criteria
Exclusion criteria: patient refusal, patients with anomalous spine ,patients with contraindication to spinal anesthesia eg coagulopathy , thrombocytopenia , allergy to local anesthetic and those on steroid or serotonin related medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of intravenous administeration of dexamethasone and combination of dexamethasone with ondansetron on subarachnoid block induced hypotension ( primary outcome) in patients undergoing lower limb orthopedic surgeries Timepoint: at 0 min ( baseline just at induction) , 5 min , 10 min, 20 min, 30 min 60 min, 90 min , 120 min , 2.5 hours, 3 hours, 3.5 hours, 4 hours, 4.5 hours , 5 hours , 5.5 hours , 6 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| post operative nausea vomitingTimepoint: 24 hrs | — |
Countries
India
Contacts
Public ContactDR SOPHIYA ARORA
GOVERNMENT MEDICAL COLLEGE BHAVNAGAR GUJARAT
Outcome results
None listed