Efficacy of Mupirocin Nasal irrigation as compared to saline nasal irrigation in acute rhinosinusitis

Efficacy of Mupirocin Nasal irrigation versus saline nasal irrigation in acute rhinosinusitis a randomized double blind study - Not applicable

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056583

Enrollment

Registered

2023-08-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J019- Acute sinusitis, unspecified

Interventions

Intervention1: Mupirocin nasal wash: 15 gram of mupirocin to be added to 500 ml normal saline.patient advised to do nasal wash with 25 ml of solution in each nostril twice a day for 5 days.symptomatic

Eligibility

Inclusion criteria

Inclusion criteria: Patient presenting with acute rhinosinusitis in ENT OPD, AVMC&H Age between 18 to 60 years Patient willing to give informed and written consent Patient willing to follow up

Exclusion criteria

Exclusion criteria: Symptoms for more than 4 weeks Critically ill patients Patient with asthma and any other allergic condition. 4. Previous history of any nose surgery.

Design outcomes

Primary

Measure	Time frame
Mupirocin nasal irrigation will provide better symptomatic relief compared to saline nasal irrigation in case of acute rhinosinusitisTimepoint: Patients will be evaluated for symptomatic scores at day 0,5and 10	—

Secondary

Measure	Time frame
Duration of treatment will be less with mupirocin nasal washTimepoint: Number of days systemic antibiotics given to the patient will be counted & compared	—

Countries

India

Contacts

Public ContactBharat bhushan

Aarupadai veedu medical college and hospitals

Atulbage25@gmail.com9443292716

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026