Comparison of haemodynamic parameters following two regimes of fractionated doses of Levobupivacaine in lower segment caesarean section under spinal anaesthesia.

Comparative evaluation of haemodynamic parameters following two regimes of fractionated doses of levobupivacaine for spinal anaesthesia in patients of lower segment caesarean section -A randomized, comparative, controlled study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056548

Enrollment

105

Registered

2023-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparative evaluation of haemodynamic parameters following two regimes of fractionated doses of levobupivacaine for spinal anaesthesia in patients of lower segment caesarean section-A

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for LSCS under spinal anaesthesia 2. ASA class II 3. Age 18-35 years 4. Height-140-170cms 5. BMI 6. Uncomplicated singleton pregnancies 7. Patient having systolic blood pressure between 110-130mm of Hg

Exclusion criteria

Exclusion criteria: 1. Patient having history of any systemic illness of cardiovascular system, respiratory system, endocrine, renal or hepatic disorders. 2. Fetal distress (as diagnosed by obstetrician) 3. BMI >30% kg / m2

Design outcomes

Primary

Measure	Time frame
To compare the number of patients requiring mephentermine to maintain systolic blood pressure Â±20% of baseline value in three groups. (Two groups of fractionated doses & one group of bolus dose). Timepoint: Perioperatively till 2 hours in same setting	—

Secondary

Measure	Time frame
To compare total requirement of mephentermine among three groups To compare haemodynamic parameters HR SBP DBP MAP To compare time of onset & regression of sensory & motor block in three groups To compare neonatal outcome by APGAR score at 1 min 5 min & 10 min Timepoint: Till 2 hours post operative period	—

Countries

India

Contacts

Public ContactDr Mahendra Kumar

Department of Anaesthesia,School of Medical Sciences and Research and Sharda Hospital

mahendramohit@yahoo.com9839963805

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026