To check the efficacy of mepivacaine as supplemental intraligamentary injection after failed inferior alveolar nerve block in symptomatic irreversible pulpitis paients

Effect Of Oral Pre-Operative Aceclofenac And Supplemental Intraligamentary Mepivacaine Injection On The Anaesthetic Efficacy Of Failed Inferior Alveolar Nerve Block In Patients With Symptomatic Irreversible Pulpitis In Manibular Molars: A Prospective, Double Blind, Placebo-Controlled, Randomized Clinical Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056538

Enrollment

120

Registered

2023-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Mepivacaine: Two groups receive Mepivacaine(Scandonest 3% plain mepivacaine)- 1.7ml injected through intraligamentary route at a rate of 1ml/min. Control Intervention1: Articaine: Two

Eligibility

Inclusion criteria

Inclusion criteria: Patients are in good health, patients should have symptomatic irreversible pulpitis in one of their mandibular molars, patients can understand heft-parker visual analogue scale, patients able to sign informed consent.

Exclusion criteria

Exclusion criteria: Administration of analgesics within 12 hr before taking study drug, allergies to aceclofenac, mepivacaine or articaine or sulphites, pregnant or lactating women, patients with introral lesion at the site of injection

Design outcomes

Primary

Measure	Time frame
Anaesthetic efficacy & pain reduction would be assessed using Heft-Parker Visual Analogue Scale.Timepoint: It will be assessed at pre-opearatively, after inferior alveolar nerve block, access into dentin, and access into pulp chamber.	—

Secondary

Measure	Time frame
No secondary outcomeTimepoint: .	—

Countries

India

Contacts

Public ContactSusmita Ghosh

JSS Dental College And Hospital

dr.parasmullj@jssuni.edu.in9845854977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026