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Effect of growth factor derived from patients blood on pulp in teeth with deep caries

Evaluation of Concentrated Growth Factor (CGF)- Biodentine Combination as a Direct Pulp Capping Agent in Cariously exposed Permanent teeth- An Observational Study. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056437
Enrollment
45
Registered
2023-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Concentrated Growth Factor and Glass ionomer cement: 2mm Concentrated Growth Factor and 2mm Glass ionomer cement for 3months, 6 months and 1 year Intervention2: Concentrated Growth Fac

Sponsors

SRM Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age group 18-45 years of either gender, under ASA category I and II 2. Maxillary and Mandibular Premolars and Permanent Molars with symptoms of Reversible Pulpitis and Radiographic evidence of deep caries approximating pulp. 3. No evidence of widening of periodontal ligament, absence of any furcation radiolucency and periapical pathology. 4. Absence of tenderness to percussion 5. Positive response to cold and electric pulp testing 6. Patients with no systemic illnesses 7. Periodontally healthy individuals

Exclusion criteria

Exclusion criteria: 1. Teeth with Symptoms of Irreversible pulpitis and Pulp necrosis 2. Negative response to cold and electric pulp testing 3. Evidence of Periapical pathology 4. Periodontally compromised teeth 5. Patients with bleeding disorders 6. Pregnant women, in view of requirements for radiographs

Design outcomes

Primary

MeasureTime frame
To check the vitality of the toothTimepoint: 3months, 6 months & 1 year

Secondary

MeasureTime frame
Dentin bridge formationTimepoint: 6 months & 1 year

Countries

India

Contacts

Public ContactDr Monisha Khatri

SRM Institute of Science and Technology

mahalaxr@srmist.edu.in9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026