Health Condition 1: F028- Dementia in other diseases classified elsewhere
Conditions
Interventions
Intervention1: Transcranial Direct Current Stimulation: The active tDCS will involve 30-minutes of direct current at the intensity of 2 milliamperes (mA)
area of the dorsolateral prefrontal cortex, ap
Sponsors
Department of Health Research
Eligibility
Inclusion criteria
Inclusion criteria: Alzheimer disease diagnosed with NINDCS or DSM 5 criteria with MMSE score more than 16
Exclusion criteria
Exclusion criteria: 1.Participants with unstable medical conditions, serious metabolic and/or cardiac diseases, alcoholism, focal neurological disorders (e.g., epilepsy, stroke, brain injury or tumor) and associated psychiatric disorders 2.Using hypnotics and benzodiazepines up to 2 weeks before the start of the study 3.With any condition (e.g., communication, sensory, or motor deficits) that could significantly interfere with the neuropsychological assessment 4.Exclusion criteria relating to contraindications of neurostimulation will be applied, following the safety guidelines: (a) using psychoactive drugs (b) having implanted metallic or electronic devices; (c) having a cardiac pacemaker, seizures, acute eczema under the electrodes; and (d) the presence of tumors, epilepsy, or substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global Cognitive PerformanceTimepoint: 1,2,4,12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Depressive SymptomsTimepoint: 1,2,4,8 weeks;Multi Domain dysfunctionTimepoint: 1,2,4,8 weeks;Quality of LifeTimepoint: 0,8 weeks;Zarit Burden InterviewTimepoint: 0,12 weeks | — |
Countries
India
Contacts
Public ContactManushree Gupta
VMMC Safdarjung Hospital
Outcome results
None listed