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Comparison of topical steroid ointment with Cardemom extract gel in treatment of oral ulcers.

Comparative evaluation of the efficacy of cardamom extract (10%) gel and Clobetasol propionate ointment for the management of Oral Lichen Planus- A double blinded randomized control trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056425
Enrollment
60
Registered
2023-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L438- Other lichen planus

Interventions

Intervention1: Cardemom extract 10% gel: Topical application of the gel on the oral mucosa thrice daily after breakfast, lunch and dinner for 60 days will be advised. Sufficient quantity of the gel wi

Sponsors

Dr Prashant Varkey
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients clinically diagnosed with Oral Lichen planus (according to Andreason criteria) with fine white radiating striae bilaterally along with burning sensation. 2. Patients above 18 years. 3. Patients who are willing to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Patients with any other potentially malignant disorders other than Oral Lichen Planus and under treatment for the same. 2. Patients who are allergic to Clobetasol propionate and Cardemom extract topical preparation. 3. Patients with any other systemic disease. 4. Pregnant and lactating females. 5. Patients who have already undergone treatment for Oral Lichen planus (within 3 months)

Design outcomes

Primary

MeasureTime frame
Reduction in the intensity of burning sensation and reduction in the size of the lesion.Timepoint: 15 days, 30 days, 45 days, 60 days

Secondary

MeasureTime frame
Whether Cardemom extract 10% gel can or cannot be used as an alternative treatment modality for the management of Oral Lichen Planus and whether it has comparable effects of Clobetasol propionate will be known.Timepoint: 15 days, 30 days, 45 days, 60 days

Countries

India

Contacts

Public ContactDr Jayraj Malik

KLE VK Institute of Dental Sciences

drshalukids@rediffmail.com9449019639

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026