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Significance of blood cell counts ratio that is NLR (Neutrophil-to-Lymphocyte Ratio) and PLR (Platelet-to-Lymphocyte Ratio) in predicting Post-operative readmissions, ICU stay and reinterventions and correlate to stage of the disease in final reports in cases of Gastro-intestinal cancers.

Significance of NLR (Neutrophil-to-Lymphocyte Ratio) and PLR (Platelet-to-Lymphocyte Ratio) in predicting Post-operative complications and Pathological outcomes in cases of Gastro-intestinal cancers. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056403
Enrollment
150
Registered
2023-08-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15-C26- Malignant neoplasms of digestive organs

Interventions

None listed

Sponsors

Dr. Atishay Agarwal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Resectable Primary GI cancer patients undergoing elective surgery. 2.Both open and minimal invasive surgery. 3.All patients above 18 years of age.

Exclusion criteria

Exclusion criteria: 1.Preoperative radiotherapy and/or chemotherapy. 2.Emergency GI malignancy surgeries. 3.Concurrent and recent documented systemic infections. 4.Patient unfit for surgery. 5.Patients on antiplatelet therapy within the previous 3 months. 6.Recent Blood transfusion. 7.Patients on steroid therapy. 8.Recurrent or Metastatic GI cancer. 9.Patients with blood malignancies and multiple myeloma.

Design outcomes

Primary

MeasureTime frame
Correlation of inflammatory cell ratio (NLR & PLR) with Post-operative Outcomes. Timepoint: 30 days of postoperative period

Secondary

MeasureTime frame
Lymph-nodes positivity. Timepoint: 30 days of postoperative period;Lympho-vascular involvement.Timepoint: 30 days of postoperative period;Pathological TNM stage of GI cancers. Timepoint: 30 days of postoperative period;Short term post-operative outcomes- 1. Length of hospital stay. 2. Length of ICU stay. 3. Readmissions & Reinterventions. Timepoint: 30 days of postoperative period;Tumour grade & differentiation. Timepoint: 30 days of postoperative period

Countries

India

Contacts

Public ContactDr Raghavendra

Kasturba Medical College and Kasturba Hospital, Manipal

dinesh.bv@manipal.edu9448654410

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026