Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nebulisation: Nebulisation will be done 30 minutes prior to surgery
Control Intervention1: Lignocaine: Nebulisation with 4% lignocaine at 3mg/kg in 5ml NS
Control Intervention2: Dexmede
Sponsors
Dr Thomas Joseph
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I and II, Elective surgeries under general anaesthesia requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: 1. Anticipated difficult airway 2. Patients with BMI >30kg/m2 3. Patients with known allergy to dexmedetomidine or lignocaine 4. Patients with cardiovascular and cerebrovascular diseases 5. Pregnancy 6. Patients with basal heart rate 7. Patients on beta blockers 8. Patients requiring more than one attempt at intubation 9. Laryngoscopy and intubation time more than 30 seconds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the change in hemodynamic parameters which includes Mean arterial pressure Systolic blood pressure Diastolic blood pressure heart rate at different time intervalsTimepoint: T0 Before nebulisation Tn After nebulization T1 1 min after intubation T3 3 min after intubation T5 5 min after intubation T10 10 min after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the Rate Pressure Product that is Heart rate multiplied by Systolic blood pressure among the two groups To compare any adverse effects like sedation hypotension bradycardia & allergic reactions in the two groups Timepoint: Tn After nebulization T1 1 min after intubation T3 3 min after intubation T5 5 min after intubation T10 10 min after intubation | — |
Countries
India
Contacts
Public ContactDr Thomas Joseph
St Johns Medical College Hospital Bengaluru
Outcome results
None listed