Addition of adjuvants Fentanyl Vs Buprenorphine in Spinal anesthesia with hyperbaric Levobupivacaine in females undergoing LSCS.

Addition of Fentanyl Vs Buprenorphine to hyperbaric levobupivacaine for sub arachnoid block in the pts undergoing lower section caesarean section. - NIL

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056356

Enrollment

Registered

2023-08-10

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Subarachnoid block: 2.5ml heavy Levobupivacaine (12.5mg) 15 mcg Fentanyl 45 mcg Buprenorphine Sensory and motor block onset in minutes.Hemodynamic changes every 2 minutes for 1st 20 m

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1-2, posted for LSCS

Exclusion criteria

Exclusion criteria: patient refusal, drug allergy, any contraindication to spinal anesthesia.

Design outcomes

Primary

Measure	Time frame
To compare efficacy of these 2 adjuvants in respective with intra-operative & post-operative hemodynamic parameters & analgesia.Timepoint: Sensory block: onset till T4 level & post operative 2 level regression (T4 to L1). Duration of analgesia. Time of Rescue analgesia. Motor block: onset degree of block then postoperative every 30 mins till Bromage 0. Monitoring:Intra operatively HR, RR, BP, SPO2 every 2min for the first 20min and then 10min till end of case APGAR SCORE:1 minute & 5 minute of birth of baby	—

Measure

Time frame

To compare efficacy of these 2 adjuvants in respective with intra-operative & post-operative hemodynamic parameters & analgesia.Timepoint: Sensory block: onset till T4 level & post operative 2 level regression (T4 to L1). Duration of analgesia. Time of Rescue analgesia. Motor block: onset degree of block then postoperative every 30 mins till Bromage 0. Monitoring:Intra operatively HR, RR, BP, SPO2 every 2min for the first 20min and then 10min till end of case APGAR SCORE:1 minute & 5 minute of birth of baby

—

Secondary

Measure	Time frame
To monitor for any side-effects, which may occur & treat them immediatelyTimepoint: VAS SCORE: preoperative, Immediate postoperative, 2 level regression time, Rescue analgesic time.	—

Countries

India

Contacts

Public ContactKavita Kadyan

NC Medical College and Hospital Israna Panipat Haryana

drmmprao1@gmail.com8699921884

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026