Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
None listed
Sponsors
Dr Farhan Shaikh
Eligibility
Inclusion criteria
Inclusion criteria: All patients intubated for respiratory failure and ventilated on Pressure-control mode of ventilation shall be included in the study from 1-month age till 18-years age.
Exclusion criteria
Exclusion criteria: 1. Children with neuromuscular diseases, 2. Those who got extubated within 24-hours of intubation. 3. Those who needed HFOV or ECMO within first 36 hours of admission 4. Those who got intubated and ventilated in outside hospitals for more than 12 hours 5. Children with immunodeficiency 6. Post operative children following Liver or Renal Transplants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Driving pressure and Mechanical Power measured in first 36-hours of intubation with 28-day ventilator-free days in a heterogeneous group of mechanically ventilated childrenTimepoint: Driving pressure and Mechanical Power measured in first 36-hours of intubation with 28-day ventilator-free days. | — |
Secondary
| Measure | Time frame |
|---|---|
| calculate Mechanical Power Normalized to body weight (NorMP) and Mechanical Energy and their association with 28-days ventilator free days. Association with other outcome parameters like PICU length of stay and mortality will be studied. Sub group analysis amongst different disease categories (normal lung, restrictive lung disease, obstructive lung disease, mixed disease) will also be performed Timepoint: at 12 and 24 hours | — |
Countries
India
Contacts
Public ContactDr Farhan Shaikh
Rainbow Childrens hospital, Road no 2, Banjara Hills, Hyderabad
Outcome results
None listed