To study the effect of bhunimbadi churna vati in alcoholic hepatitis

Evaluation of efficacy of bhunimbadi churna vati in alcohol hepatitis - a single arm experimental study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056282

Enrollment

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K701- Alcoholic hepatitis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Able to provide written consent. 2. Male or female patients between 22- 55 yrs of age. 3. AST Value 50u/l to 400u/l 4. Total bilirubin in the range of 2 mg/dl to 15mg/dl. 5. AST:ALT > 1.5

Exclusion criteria

Exclusion criteria: 1.Other liver pathology like viral hepatitis, drug induced hepatitis, non-alcoholic hepatitis, immunocompromised patients. 2.Patient with alcoholic withdrawal symptoms such as hallucination, abusive, agitated & aggressive behavior. 3. K/C/O - liver cirrhosis, liver cancer & ascites. 4.K/C/O - renal disorder, cardiac disorder, hypertension and other chronic disorder, endocrinological disorder. 5.K/C/O - Hemochromatosis, Wilson disease and other autoimmune disorder. 6.Pregnant & lactating women.

Design outcomes

Primary

Measure	Time frame
SUBJECTIVE CRITERIA- 1.Twacha-peetavarna (Yellowish discoloration of skin) 2.Nakha-peetavarna (Yellowish discoloration of nails) 3.Peeta-netrata(Yellowish discoloration of eyes) 4.Peeta mutra varna (Yellowish discoloration of urine) 5.Peet-shakrit(Yellowish discoloration of stool) 6.Mukha- peetata (Yellowish discoloration of face) 7.Jwar (Fever) 8.Shudhamandya (Loss of appetite) 9.Daurbalya (Weakness) 10.Aruchi (Loss of taste) 11.Hrullas (Nausea) OBJECTIVE CRITERIA- CBC,LFTTimepoint: Baseline and After 4 weeks	—

Measure

Time frame

SUBJECTIVE CRITERIA- 1.Twacha-peetavarna (Yellowish discoloration of skin) 2.Nakha-peetavarna (Yellowish discoloration of nails) 3.Peeta-netrata(Yellowish discoloration of eyes) 4.Peeta mutra varna (Yellowish discoloration of urine) 5.Peet-shakrit(Yellowish discoloration of stool) 6.Mukha- peetata (Yellowish discoloration of face) 7.Jwar (Fever) 8.Shudhamandya (Loss of appetite) 9.Daurbalya (Weakness) 10.Aruchi (Loss of taste) 11.Hrullas (Nausea) OBJECTIVE CRITERIA- CBC,LFTTimepoint: Baseline and After 4 weeks

—

Secondary

Measure	Time frame
A.Changes in Subjective parameters like 1.Twacha peetavarna 2.Nakha peetavarna 3.Peeta netrata 4.Peeta mutra varna 5.Peeta shakrit 6.mukha peetata 7.Jwar 8.Shudhamandya 9.Daurbalya 10.Aruchi 11.Hrullas. B.Changes in objective parameters like CBC & LFT which includes 1.serum bilirubin 2.AST-ALT ratio.Timepoint: Baseline & after 4 weeks	—

Countries

India

Contacts

Public ContactDr Amatullah Ataullah Dalvi

Dr G.D.Pol Foundation YMT Ayurvedic Medical College and Hospital, PG Institute

vd.pravin09j@gmail.com9890902106

Outcome results