The efficacy of tranexamic acid which is a drug that promotes clotting of blood , in preventing blood loss in patients undergoing intertrochanteric surgeries

Evaluation of efficacy of tranexamic acid on blood loss in surgically managed Intertrochanteric Fractures - NILL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056281

Enrollment

100

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V00-Y99- External causes of morbidity

Interventions

Intervention1: Tranexamic acid: 2g injection of tranexamic acid given through drain post operatively Control Intervention1: Placebo: 20 ml normal saline given through drain post operatively

Eligibility

Inclusion criteria

Inclusion criteria: Patients of intertrochanteric fractures requiring fixation with DHS/DCS

Exclusion criteria

Exclusion criteria: • Psychiatric patients • Patients in whom stabilization with implants other than DHS/DCS • Any bleeding disorder like haemophilias, deranged international normalized ratio • Any previous history of adverse reaction or allergy to TXA • Congenital or acquired coagulopathy • Recent history of thrombo-embolic episode • Implant removal procedure

Design outcomes

Primary

Measure	Time frame
To assess the efficacy of Tranexamic acid in reducing intra and post-operative blood loss volume(during first 48 hours) in patients undergoing intertrochanteric fractures surgeriesTimepoint: To assess the efficacy of Tranexamic acid in reducing intra and post-operative blood loss volume(during first 48 hours) in patients undergoing intertrochanteric fractures surgeries	—

Secondary

Measure	Time frame
To assess the reduction of requirement of blood transfusion both inra-operative and during first 48 hours post surgery. To assess any thromboembolic eventsTimepoint: first 48 hours post surgery 3 months post surgery	—

Countries

India

Contacts

Public ContactDr Goutam Goyal

Pt BD Sharma PGIMS Rohtak

pradyumnakm1@gmail.com7988153640

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026