To study the ocular perfusion pressure between two general anaesthesia maintenance protocols in adults scheduled for elective thoracolumbar spine surgeries.

Comparison of ocular perfusion pressure between two general anaesthesia maintenance protocols in adults scheduled for elective thoracolumbar spine surgeries in prone position: A prospective, randomized controlled trial. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056268

Enrollment

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Propofol: propofol infusion at the rate of 50-100 mcg/kg/min intravenously, for the maintenance of anaesthesia, titrated to response entropy of 45-60 in a mixture of oxygen and nitrous

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA PS 1 and 2 2. Scheduled for elective thoracolumbar spine surgeries in prone position.

Exclusion criteria

Exclusion criteria: 1. Uncontrolled hypertension 2. Uncontrolled Diabetes mellitus 3. History of allergic reactions to any drugs used in the study. 4. Baseline IOP > 30 millimeters of mercury 5. Significant prone provocative test. 6. Pre-existing glaucomatous cupping. 7. Pre-existing primary-angle closure glaucoma. 8. Previous eye surgeries. 9. Previous eye disease.

Design outcomes

Primary

Measure	Time frame
To compare ocular perfusion pressure at predetermined time points perioperatively between two groups of patients receiving either propofol or desflurane for the maintenance of anesthesia during elective thoracolumbar spine surgeries in prone position.Timepoint: Five minutes after extubation.	—

Secondary

Measure	Time frame
1. To compare mean arterial pressure(MAP) at predetermined time points between two groups of patients. 2. To compare the number of hypotensive episodes between the two groups of patients(defined as MAP 65 mm Hg for more than 5 minutes intraoperatively)Timepoint: Thirty minutes after extubation.	—

Countries

India

Contacts

Public ContactGargi A V

All India Institute of medical sciences, Bathinda, Punjab

doctorjyotisharma@yahoo.in9968583915

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026