Evaluation of copper and zinc quantity in saliva, released from copper oxide and zinc oxide nanoparticles coated attachments used for fixed orthodontic treatment in patients having tooth malalignment

Evaluation Of The Cytotoxicity, Surface Characteristics And Biocompatibility Of Copper Oxide And Zinc Oxide Nanocoated Orthodontic Brackets: An observational study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056249

Enrollment

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Copper oxide nanoparticle coated orthodontic brackets: Copper oxide nanocoated brackets will be bonded in patients undergoing fixed orthodontic treatment Control Intervention1: Zinc oxi

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients needing bonding in upper and lower arch with 0.022 “slot MBT prescription stainless steel orthodontic brackets and banding in first molars with no other auxiliaries required other than TPA in the maxilla. 2. Patients who do not require therapeutic extraction of teeth 3. Patients willing to give consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Presence of systemic disease 2. Presence of smoking habit, habit of chewing gums 3. Use of anti-inflammatory or antibiotic medication 4. Patients with history of Copper or Zinc allergy

Design outcomes

Primary

Measure	Time frame
Salivary ion release of Copper & Zinc nanoparticles must be within non toxic ranges.Timepoint: T0 baseline T1 1st week after bonding T2 1st month after bonding T3 3rd month after bonding	—

Secondary

Measure	Time frame
Surface changes of coated nanoparticle bracketsTimepoint: T1 before bonding T2 after debonding	—

Countries

India

Contacts

Public ContactSangeetha Duraisamy

Department of orthodontics . SRM dental college

sangeetha.guhan@yahoo.com9789000386

Outcome results