Comparison of safety and efficacy between Propofol alone and Propofol with Ketamine and Dexmedetomidine while being used as an anesthetic agent in TIVA during ERCP procedure

Efficacy and safety during Endoscopic Retrograde Cholangio-Pancreatography under Total Intravenous Anesthesia-Propofol alone versus Propofol supplemented with Dexketa, a comparative study in Medical College Kolkata

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056241

Enrollment

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K831- Obstruction of bile duct

Interventions

Intervention1: Propofol: Propofol 30mg bolus slow IV, after 10 mins while negotiating scope 50mg slow IV, and then repeated according to requirements throughout the duration of surgery Control Interve

Eligibility

Inclusion criteria

Inclusion criteria: Physical status ASA-PS 1 and ASA-PS 2 Having no anticipated difficult airway

Exclusion criteria

Exclusion criteria: Patient refusal AKI,CKD,Low Ejection Fraction, Uncontrolled Diabetes Undergoing emergency procedure Known allergy to drugs to be used in the study Previous bleeding disorder or coagulopathy Administration of any sedative or narcotics within 24 hours Duration more than 60 minutes

Design outcomes

Primary

Measure	Time frame
A decrease in heart rate when Dexmedetomidine is usedTimepoint: Baseline, 4 weeks, 8 weeks	—

Secondary

Measure	Time frame
Dose of Propofol required will be much less when used along with Ketamine & DexmedetomidineTimepoint: BASELINE 4 WEEKS AND 8 WEEKS	—

Countries

India

Contacts

Public ContactDr Debankita Das

Medical College Kolkata

debasish2801@gmail.com9231319202

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026