A clinical to compare the onset of drug action time of intravenous ketamine (an anesthetic agent) in pediatric patients with or without congenital heart disease.

Comparative evaluation of induction time using intravenous ketamine in pediatric patients with or without congenital heart disease. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056235

Enrollment

102

Registered

2023-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I52- Other heart disorders in diseasesclassified elsewhere

Interventions

Intervention1: KETAMINE in pediatric patients with congenital heart disease.: Intravenous ketamine 2mg/kg in pediatric patients with congenital heart disease. Total duration of this study is 1.5 years

Eligibility

Inclusion criteria

Inclusion criteria: 1.Pediatric cardiac surgical patients aged less than 6 years with Congenital heart disease. 2.Pediatric surgical patients aged less than 6 years without Congenital heart disease

Exclusion criteria

Exclusion criteria: Neonates, Emergency surgery,redo surgery,Patient in shock,sepsis or DIC, Patient in congestive heart failure, Renal dysfunction,severe liver disease,Condition affecting basal metabolic rate i.e, febrile illness,hypothyroidism,hyperthyroidism,pheochromocytoma, Patient on mechanical ventilation,Patient with ventricular dysfunction,Patient with valvular and obstructive lesions,Patient with increased Intra cranial tension and increased intra occular tension

Design outcomes

Primary

Measure	Time frame
To compare induction time of intravenous anesthesia using ketamine, as determined by the time taken for loss of eyelash reflex & onset of nystagmus in patients with & without congenital heart disease. Timepoint: At the time of onset of nystagmus and at the time of loss of eyelash reflex	—

Secondary

Measure	Time frame
To observe corresponding BIS values during induction of anesthesia with ketamine in patients with congenital heart disease. Timepoint: At Baseline,at the time of onset of nystagmus & at the time of loss of eye reflex	—

Countries

India

Contacts

Public ContactDr Thiruselvan T

All India Institute of Medical Sciences,New Delhi

thiruselvan777@gmail.com9629197528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026