To study the action of dexmedetomidine drug given through the nostrils on changes in heart rate and blood pressure in laparoscopic surgeries.

Study of effect of intranasal dexmedetomidine on stress response to pneumoperitoneum in laparoscopic surgeries: A one year double blinded hospital based randomised clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056200

Enrollment

Registered

2023-08-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: INTRANASAL DEXMEDETOMIDINE: After obtaining the approval of ethical committee, written informed consent will be taken from patients meeting the inclusion criteria after pre anaesthetic

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA physical status 1 and II 2) Patients undergoing laparoscopic surgeries under general anaesthesia 3) Provides consent

Exclusion criteria

Exclusion criteria: 1) Patient refusal or unable to give consent 2) ASA physical status III & above 3) Patients with nasal deformities. 4) Patients allergic to study drug.

Design outcomes

Primary

Measure	Time frame
To determine the effect of intranasal dexmedetomidine on stress response to pneumoperitoneum in laparoscopic surgeries.Timepoint: Baseline(Preop),5 mins before Pneumoperitoneum(T0),At the time of Pneumoperitoneum(TP),and then every 5mins thereafter[5mins (T5),10mins (T10),15mins (T15),20mins (T20),25mins (T25),30mins (T30)]	—

Secondary

Measure	Time frame
To determine the side effects of study drug if any.Timepoint: UPTO 6 HOURS POST OP.	—

Countries

India

Contacts

Public ContactVarsha B Shetty

Jawaharlal Nehru Medical College, Belagavi

vandanagogate@gmail.com9844083030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026