Health Condition 1: O- Medical and Surgical
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18 to 65 years 2. Mechanical ventilation for minimum 48 hours an
Exclusion criteria
Exclusion criteria: 1. Patients with history of neuromuscular disease 2. Patients with history suggestive of diaphragmatic dysfunction 3. Patients with chest tube in situ 4. Patients with pneumothorax & pneumomediastinum 5. Patients with chronic obstructive pulmonary disease 6. Pregnant Patients 7. Patients with known heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the Diaphragmatic Thickening Fraction (DTF) as a predictor for successful weaning in ICU patientsTimepoint: 30 minutes from spontaneous breathing trial | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum expiratory pressure (MEP) & Maximum Inspiratory Pressure (MIP) to predict successful weaningTimepoint: 5 minutes & 30 minutes from spontaneous breathing trial;The number of patients requiring Non-Invasive Ventilation (NIV) or reintubation within 24 hours of extubationTimepoint: Within 24 hours from extubation;Time to reintubation/non-invasive ventilation: Time interval between the point of extubation & the point of non-invasive ventilation/reintubation if done.Timepoint: Within 24 hours from extubation;To evaluate the Diaphragmatic Excursion (DE), Lung Ultrasound Score (LUS) & Rapid Shallow Breathing Index (RSBI) as a predictor for successful weaning in ICU patientsTimepoint: Rapid Shallow Breathing Index (RSBI) at 5 & 30 minutes of spontaneous breathing trial Diaphragmatic Excursion (DE) & Lung Ultrasound Score (LUS) at 30 minutes of spontaneous breathing trial | — |
Countries
India
Contacts
Maulana Azad Medical College