Changes in the blood gas values during the operation time of abdominal aortic surgeries with sodium bicarbonate bolus and sodium bicarbonate infusion.

Intraoperative acid-base changes with bolus administration versus continuous infusion of sodium bicarbonate during repair of abdominal aorta. - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056171

Enrollment

Registered

2023-08-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I714- Abdominal aortic aneurysm, withoutrupture

Interventions

Intervention1: Sodium bicarbonate infusion: Sodium Bicarbonate will be given as infusion at 1 mEq/kg/hr, during aortic cross clamp time period,through central line. Duration is cross clamp time. Contr

Eligibility

Inclusion criteria

Inclusion criteria: -Adult patients who are diagnosed with abdominal aortic pathologies such as Abdominal aortic aneurysm, aortoiliac occlusive disease. -All elective and emergency surgeries.

Exclusion criteria

Exclusion criteria: -Preoperative Renal replacement therapy -Patients who are placed on partial cardiopulmonary bypass.

Design outcomes

Primary

Measure	Time frame
To study Hemodynamic parameters including Heart rate blood pressure Central venous pressure EtCo2 & acid base parameters including Arterial blood pH sodium bicarbonate base deficit arterial to venous Co2 gap anion gap serum electrolytes and lactateTimepoint: intraoperative period	—

Secondary

Measure	Time frame
To study vasoconstrictor score at the time of closure of skin in abdominal aortic surgical repairTimepoint: intraoperative period	—

Countries

India

Contacts

Public ContactDodda Brahmam

Sree Chitra Tirunal Institute for Medical Sciences and Technology

dash@sctimst.ac.in9400368662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026