Skip to content

Evaluating the contractile effect of two medicines, namely carbetocin and oxytocin, on the uterus, in patients undergoing cesarean surgery

Evaluation of the uterotonic effect of Carbetocin vs Oxytocin in elective caesarean sections

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056162
Enrollment
30
Registered
2023-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: Group carbetocin: Patients will receive 100 mcg carbetocin IV after delivery of baby Control Intervention1: Group oxytocin: Patients will receive oxytocin 3 units IV followed by oxytoci

Sponsors

Amrita institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Parturient between 18 â?? 40 years undergoing elective caesarean section.

Exclusion criteria

Exclusion criteria: H/o significant Cardiac, renal or liver diseases. Hypertensive disorder of pregnancy. Multiple pregnancy. Abnormal placenta. Polyhydramnios. Fibroid complicating pregnancy. Epilepsy. General anaesthesia. Hypersensitivity to study medications and their preservatives

Design outcomes

Primary

MeasureTime frame
To compare the uterine tone with prophylactic intravenous oxytocin vs. carbetocin in parturients undergoing elective cesarean section under spinal anesthesia. Timepoint: 3 minutes

Secondary

MeasureTime frame
Hemodynamic effects including heart rate, systolic blood pressure & mean arterial pressure after administration of the drug. Requirement of further uterotonic agents. Adverse effects. Timepoint: Till 15 minutes after delivery of baby

Countries

India

Contacts

Public ContactDilesh Kadapamannil

Amrita Institute of medical sciences

dr.dilesh@gmail.com09994202788

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026