Comparison between getting loss back outline of inhalational agents and in person getting cares undergoing laparoscopic surgeries-A forward look as by chance medical learning process

Comparison of recovery profile of Desflurane & Sevoflurane in patients undergoing laparoscopic surgeries-A prospective randomized clinical study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056108

Enrollment

Registered

2023-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K402- Bilateral inguinal hernia, withoutobstruction or gangrene Health Condition 2: K819- Cholecystitis, unspecified Health Condition 3: O- Medical and Surgical Health Condition 4: K37- Unspecified appendicitis

Interventions

Intervention1: DESFLURANE: In laparoscopic procedure with duration of 2 hours, patient maintained with desflurane after intubation. Patient recovery profile will be monitored after vapourizer shutoff

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective laparoscopic surgery (laparoscopic cholecystectomy, laparoscopic hernia repair) duration of one and half to two hours under General anaesthesia. 2.Age 18 - 65 years of either gender. 3.BMI less than 30kg/m2 4.Patients with ASA physical status I-II. 5.Patient belonging to Mallampatti grading I-II on airway assessment.

Exclusion criteria

Exclusion criteria: 1.Inability or refusal to follow the study protocol. 2. Patient with uncontrolled medical conditions like hypertension, diabetes mellitus, renal failure., etc 3.Patient with cardiac, renal, respiratory disorders. 4. Patients with hypotension and shock. 5.Patient having neuro psychiatric disorders, H/o drug abuse

Design outcomes

Primary

Measure	Time frame
To compare post-operative recovery profile using Fast Track Criteria(FTC)Timepoint: FTC monitored at the time of extubation & for every 10 mins until one hour of post extubation followed by 4 hours of extubation	—

Secondary

Measure	Time frame
1.To monitor & maintain BIS between the values 40-60 by titrating concentration of Desflurane and Sevoflurane 2.To monitor and maintain EtCO2 in the range of (25-35mmHg) 3.To Monitor intraoperative hemodynamic stability by monitoring systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean arterial pressure (MAP), Pulse rate (PR), Peripheral oxygen saturation (SpO2) and maintain them within 20% of baseline value 4.To calculate the requirement of incremental dose of fentanyl 5.To observe side effects and complications following General anaesthesia and treat it accordingly Timepoint: intra operative hemodynamics,ETCO2 monitored every 15 mins .BIS value monitored through out the procedure & inhalational want to titrate according to BIS value and also want to monitor at the time of extubation.	—

Measure

Time frame

1.To monitor & maintain BIS between the values 40-60 by titrating concentration of Desflurane and Sevoflurane 2.To monitor and maintain EtCO2 in the range of (25-35mmHg) 3.To Monitor intraoperative hemodynamic stability by monitoring systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean arterial pressure (MAP), Pulse rate (PR), Peripheral oxygen saturation (SpO2) and maintain them within 20% of baseline value 4.To calculate the requirement of incremental dose of fentanyl 5.To observe side effects and complications following General anaesthesia and treat it accordingly Timepoint: intra operative hemodynamics,ETCO2 monitored every 15 mins .BIS value monitored through out the procedure & inhalational want to titrate according to BIS value and also want to monitor at the time of extubation.

—

Countries

India

Contacts

Public ContactDr Swati A Bhatt

Government medical college, Baroda

drswatibhatt2015@yahoo.com9879372038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026