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Effect of Vitamin C on surgical stress response in laparoscopic gynaecological surgery.

Effect of preoperative intravenous Ascorbic acid on serum levels of C - Reactive Protein as a marker of surgical stress response in laparoscopic gynaecological procedure under general anaesthesia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056106
Enrollment
56
Registered
2023-08-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Intravenous Ascorbic Acid: Intravenous Ascorbic Acid 1gm 20 minutes prior to intubation in 500ml Normal saline infusion Control Intervention1: Intravenous normal saline 1o ml: Intraveno

Sponsors

Atal Bihari Vajpaee Institute Of Medical Sciences And Dr Ram Manohar Lohia Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women aged 18 To 65 years posted for Elective Diagnostic Hysterolaparoscopic surgery. ASA Class I AND II

Exclusion criteria

Exclusion criteria: Patients with endocrine morbidities such as Diabetes Mellitus, Hypopituitarism, Cushings disease Patients with Hypertension. Heart diseases such as Coronary Heart disease, Valvular Heart disease. Patients already on Steroid treatment.

Design outcomes

Primary

MeasureTime frame
Serum Level Of C- Reactive ProteinTimepoint: T0 Baseline - Just After Cannulation T1 - 5 Minutes After Creating Pneumoperitonium T2 - Immediately After Extubation T3 - 12 Hours After Extubation—

Secondary

MeasureTime frame
Hemodynamic Stress Response.( Heart Rate, Systolic Blood Pressure , Diastolic Blood Pressure, Mean Arterial Pressure)Timepoint: T0 Baseline - Just After Cannulation T1 - 5 Minutes After Creating Pneumoperitonium T2 - Immediately After Extubation T3 - 12 Hours After Extubation;Levels Of A. Blood Sugar B. Serum CortisolTimepoint: T0 Baseline - Just After Cannulation T1 - 5 Minutes After Creating Pneumoperitonium T2 - Immediately After Extubation T3 - 12 Hours After Extubation—

Countries

India

Contacts

Public ContactDr Namita Arora

Atal Bihari Vajpaee Institute Of Medical Sciences And Dr Ram Manohar Lohia Hospital

namitaarora16@yahoo.com9868219619

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026