A study to compare the postoperative analgesic efficacy of dexamethasone as an adjuvant to ropivacaine in incision site infiltration in patients undergoing elective supratentorial craniotomy

A randomised comparative study on postoperative analgesic efficacy of dexamethasone as and adjuvant to ropivacaine in incision site infilration in patients undergoing elective supratentorial craniotomy at S.M.S Medical College and Attached Group of Hospitals Jaipur. - Nil

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056100

Enrollment

Registered

2023-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Incision site Infiltration: A randomised comparative study on postoperative analgesic efficacy of dexamethasone as an adjuvant to ropivacaine in incision site infiltration in patients u

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients given informed and written consent 2. 20 - 50 years of age of either gender 3. ASA physical status of I-II 4. Scheduled for elective supratentorial tumour craniotomy under general anaesthesia 5. Patients in whom surgeon anticipates uneventful extubation and return of consciousness, orientation as well as cooperation after extubation so that patient may correctly express the degree of pain.

Exclusion criteria

Exclusion criteria: 1.Patients with history of previous craniotomy ,psychiatric disorders,epilepsy or chronic headaches 2.BMI 35 3. Allergic to opioids,dexamethasone or ropivacaine 4.history of excessive alcohol or drug abuse 5.preoperative GCS 6. Peri-incisional infection

Design outcomes

Primary

Measure	Time frame
1. To assess & compare mean rescue analgesic consumption (diclofenac ) in between study groups. 2. To assess & compare mean time to require first rescue analgesic between study groups. 3. To assess and compare mean NRS (Numerical Rating Scale)value in between study groups.Timepoint: 0 6 12 24 hours	—

Secondary

Measure	Time frame
1.To assess & compare mean PONV scores at 0,6,12,24 hrs 2.To assess and compare PSS scores at 24 hrs 3.To assess and compare mean haemodynamic parameters at 0,6,12,24 hrsTimepoint: 0 6 12 24 hours	—

Countries

India

Contacts

Public ContactDr Sukirti Sharma

Sawai man singh medical college

drneelu13@gmail.com9782480455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026