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To assess the effect of erythropoietin (EPO)in augmentation of peri implant tissues.

Evaluation of efficacy of erythropoietin (EPO) in augmentation of peri implant soft tissues: A Randomized Controlled Clinical trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/056074
Enrollment
50
Registered
2023-08-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Micro needling along with 0.1 ml of erythropoietin injection: Micro needling will be done in keratinized tissue of implant and erythropoietin will be injected into the apical region of

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients. 2.Patients with at least one implant placed with functional restoration, with keratinized tissue 3.Patient with thin gingival phenotype. 4.Peri-implant probing depth 5.No signs of pre-existing peri-implantitis

Exclusion criteria

Exclusion criteria: 1.Patients with systemic diseases that would have influenced bone or soft tissue metabolism, 2.Smoking habit of more than one pack per day and unwillingness to stop the habit, 3.Radiotherapy and/or chemotherapy in the past 12 months 4.Unwillingness to commit to a long-term maintenance program after treatment.

Design outcomes

Primary

MeasureTime frame
Gingival augmentation of peri implant soft tissuesTimepoint: Baseline 3 months & 6 months

Secondary

MeasureTime frame
Peri-implant probing depth (PIPD),Clinical attachment level (CAL),Papillary recession height,Interproximal width (IPW),Keratinized tissue width (KTW),Gingival index (GI),Plaque index (PI),Modified sulcular bleeding index (mSBI),Patient Reported Outcome Measures (PROMS) Timepoint: Baseline,3 months and 6 months

Countries

India

Contacts

Public ContactDr Humaira Siddique

VSPM Dental College and Research Centre

drkamalk@gmail.com9850061038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026