Comparison of vasopressors for treatment of hypotension during cesarean section.

Comparison of bolus mephentermine, ephedrine and phenylephrine for the treatment of hypotension in lower segment cesarean section under spinal anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056070

Enrollment

120

Registered

2023-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: Bolus ephedrine 6mg: Bolus dose of ephedrine 6mg whenever there is blood pressure drop of more than 20 percent of baseline or blood pressure less than 90mmHG whichever is higher. Inter

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Age group of 18 â?? 35 years 2. ASA II patients with full term pregnancy 3. Elective LSCS 4. Parturient giving informed written consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Known hypertensive patients, patients on anti- hypertensive drugs & uncontrolled PIH 2. Multiple Gestations 3. Obese ( > 90 kg) or BMI >30 kg/m2 4. Short stature ( 5. Haemoglobin 6. Patients with spinal deformity or puncture site infection 7. Known hypersensitivity to any of the 3 drugs 8. Patients with bleeding diathesis or coagulopathy

Design outcomes

Primary

Measure	Time frame
Which one is a better vasopresser in LSCS under spinal anaesthesiaTimepoint: Sample size in each arm is 40 . Total sample size of 3 arms is 120.	—

Secondary

Measure	Time frame
Any side effect of drugsTimepoint: Any side effect of drugs	—

Countries

India

Contacts

Public ContactDr Tailang Bumer

TRIHMS , Naharlagun

bumerxp786@gmail.com8258819316

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026