Effect of pre-operative oral clonidine and gabapentin in patients undergoing leg fracture surgery

Effect of pre-operative oral gabapentin versus oral clonidine on postoperative analgesia in both tibia fibula fracture with open reduction and internal fixation under spinal anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056059

Enrollment

Registered

2023-08-03

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Gabapentin: Oral gabapentin 600mg will be given preoperatively 1.5hours before the Surgery and monitored for 24 hours Control Intervention1: Clonidine: Oral clonidine 150mcg will be giv

Eligibility

Inclusion criteria

Inclusion criteria: Haemodynamicaly stable patients of age group 20 to 65 years American society of anesthesiologist (ASA) grade I and II Weight range up to 20% of ideal body weight for either sex

Exclusion criteria

Exclusion criteria: History of chronic systemic disease Pregnancy Known psychiatric disorders Anticipated difficult airway Short stature Patients refusal for participation Surgery exceemore than 4 hours or requiring epidural activation

Design outcomes

Primary

Measure	Time frame
Post operative analgesiaTimepoint: 1,2,3,4,5,6,8,10,12,16,20,24 hour	—

Secondary

Measure	Time frame
Complications between gabapentin & clonidineTimepoint: 1,2,3,4,5,6,8,10,12,16,20,24 hours	—

Countries

India

Contacts

Public ContactDr Joe Stalon

Sri Manakula Vinayagar Medical College and Hospital

drbalasubbu77@gmail.com9940764982

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026