Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Cisatracurium: A comparison of Cisatracurium a newer muscle relaxant with Atracurium with regards to heamodynamic parameters and intubating conditions.
Control Intervention1: Atracurium
Sponsors
Dr Thumu Jaisheel Gabriel Joseph
Eligibility
Inclusion criteria
Inclusion criteria: 1. American society of Anaesthesiology score [ASA] I and 2 2. Both Males and Females 3. Age between 18 years and 60 years 4. Patients requiring endotracheal intubation undergoing General anaesthesia 5. Patients undergoing only Elective Procedures
Exclusion criteria
Exclusion criteria: 1. Any systemic co-morbidity including uncontrolled hypertension and diabetes, Heart block, renal impairment (serum creatinine greater than 2mg/dl, hepatic impairment (trans-aminases greater than double the normal values), psychiatric disorders like Schizophrenia and Mania 2. Patient not giving consent 3. ASA Grade 3 and Grade 4 patients 4. Patients with history of Bronchial Asthma 5. Patient on any addictive drug or allergic to any drugs used in the trial 6. Pregnant patient and lactating mothers 7. Anticipated Difficult Airway (Mallampati Class III and IV, thyromental height < 6 cm, inter-incisor distance <3cm and cervical instability.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To compare the effect of Muscle Relaxation between Atracurium & Cis Atracurium by comparing the ease of intubation 2. To compare the change in haemodynamic parameters while using either Atracurium or Cis AtracuriumTimepoint: 10 minutes after induction | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the Time interval for first maintenance dose between Atracurium & Cis atracurium 2. To compare cost effectiveness between Atracurium & Cis atracuriumTimepoint: At baseline | — |
Countries
India
Contacts
Public ContactDr Meyong Pincho Bhutia
Sikkim Manipal Institute of Medical Sciences
Outcome results
None listed