Health Condition 1: C910- Acute lymphoblastic leukemia [ALL]
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
Dr Antara Sanyal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Newly diagnosed case of acute lymphoblastic leukemia 2. Age 1-18 years 3. Treatment naïve 4. Diagnosis will be based upon the morphology and immunophenotype of the bone marrow aspirate/ peripheral blood sample
Exclusion criteria
Exclusion criteria: 1. ALL 18 years 2. Relapsed ALL, partially treated ALL 3. Burkittâ??s Leukemia 4. HIV, Hepatitis-B or Hepatitis-C positive cases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the Grade three & Grade four toxicity during ALL induction chemotherapyTimepoint: Days 1 to 7 Days 8 to 14 Days 15 to 25 Days 26 to 35 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess the quality of life at baseline & at the end of induction using the tool PedsQLâ?¢ 4.0 Generic Core (PedsQL-G) & PedsQLâ?¢ 3.0 Cancer Module (PedsQL-C); 2. To correlate QoL to toxicity during induction treatment; 3. To correlate post induction minimal residual disease (MRD) with baseline clinical characteristics & induction toxicities. Timepoint: At the beginning & end of induction chemotherapy | — |
Countries
India
Contacts
Public ContactDr Antara Sanyal
Institute of Medical Sciences and SUM Hospital, SOA
Outcome results
None listed