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Comparison Between Intralesional MMR vaccine and Intralesional Vit D in treatment of Plane Warts

Effectiveness of Intralesional MMR Vaccine and Intralesional Vitamin D3 in Treatment of Plane Warts in Tertiary Health Care Center â?? A Randomized Comparative Control Study. - NA

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/055966
Enrollment
68
Registered
2023-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B078- Other viral warts

Interventions

Intervention1: Vitamin D: Intralesional Vitamin D 2 weekly upto 4 doses and follow up until 10th week from 1st visit. Control Intervention1: MMR VACCINE: Intralesional MMR Vaccine 2 weekly upto 4 dose

Sponsors

MAMC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Sex/Age: - Either sex from 18 â?? 60 years of age 2. Patients diagnosed with multiple plane warts ( >2) based on clinical examination.

Exclusion criteria

Exclusion criteria: 1. Patients under any systemic or topical treatment of warts for the last four weeks 2. Patients with a past history of an allergic response to vaccine or drug 3. Patients with current acute febrile illness or any bacterial infection 4. Immunosuppressed patients (HIV/Immunodeficiency syndrome/Immunosuppressants agents/etc.) 5. Pregnant or lactating women 6. Patients having past history of asthma, allergic skin disorders or convulsions 7. Patient refusal for consent 8. Treating physicianâ??s decision to give other treatment modality 9. Atypical, subclinical or dysplastic types of warts

Design outcomes

Primary

MeasureTime frame
Cure rate: Complete disappearance of disease/lesion before or after completing the course of treatment.Timepoint: four doses of two weekly injections. Final outcome to be seen 4 weeks after last dose.

Secondary

MeasureTime frame
1. Partial response to both the drugs will be assessed by decrease in size & total number using Visual Analog Scale. 2. Frequency of Adverse Drug Reaction to both the drugs by using Naranjo ScaleTimepoint: 2 weekly dosage for 3 times followed by follow up after 1 month of last dose

Countries

India

Contacts

Public ContactDr Sandeep Sharma

MAMC Agroha Hisar

drshalinivrewri@gmail.com9588184568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026